Tadalafil Vs Sildenafil

Introduction: What is the difference between tadalafil and sildenafil?

Both tadalafil and sildenafil are used in the treatment of erectile dysfunction. However, there are some differences between them that should be known by patients considering the use of these medications.

Tadalafil is metabolized primarily by CYP3A4 to both its major polarity and active metabolites, whereas sildenafil is exclusively metabolized by CYP3A4 to its active metabolite.


How does Tadalafil work?

Tadalafil and sildenafil are both medications prescribed to treat erectile dysfunction. While they work similarly, there are some differences between the two drugs. Sildenafil is more preferable for patients with liver or kidney disease or heart problems. Tadalafil is not affected by these factors and so is a better choice for such patients.

Tadalafil is taken orally while sildenafil is taken as an injection into the penis. The doses of the two drugs are different. The usual dose of Tadalafil is 20-40 mg. As Tadalafil is a PDE5 inhibitor, it relaxes the blood vessels and allows more blood into the penis. This makes the penis erect.

How long does it take to get the effects of Tadalafil?

The difference between the two drugs is that tadalafil takes longer to work and lasts for a longer period of time than sildenafil.

Tadalafil also has the added benefit of preventing certain types of strokes and blood clots. It is best to take it on an empty stomach and wait at least 20 minutes after having food before taking it.

This way, it can be easier to know if you’re experiencing any side effects.


 Dosage forms of Tadalafil?

Tadalafil and Sildenafil are two drugs used to treat erectile dysfunction. Tadalafil is a little stronger than Sildenafil for some men, but it still works in the same way. A person takes this drug by mouth right before sex, with or without food. The effects of the drug will last about 4 hours. Tadalafil is the only drug approved for erectile dysfunction that is safe for women. Tadalafil is available as an oral tablet (Cialis), an oral tablet with a film over it (Viagra), and as a soft, suppository (Cenforce).


Side effects of Tadalafil

According to WebMD, Tadalafil lasts for 4-5 hours while Sildenafil lasts for 3-4 hours. The side effects (nausea, headache, lightheadedness) are also different with Tadalafil more likely to cause nausea and Sildenafil being more likely to cause headaches and lightheadedness.





How does Sildenafil work?

As the most prescribed ED drug on the market, Sildenafil is a pioneer in treating erectile dysfunction. The most important question for most patients is how it works. Let’s explore this question and examine what makes Sildenafil such an effective treatment for male impotence.

When a man is aroused, nitric oxide increases blood flow to the penis, causing the erection to last longer. Sildenafil works by mimicking nitric oxide. Sildenafil slowly increases blood flow to the penis, triggering a self-sustaining process that will lead to a strong, sustained erection.


How long does it take to get the effects of Sildenafil?

People are often curious about the length of time that the effects of Sildenafil last. To answer this question, it is important to note that there are many factors that can influence the duration of the effects of Sildenafil. For example, if someone has a higher body fat or builds up a tolerance to Sildenafil, they may not see the same effects as someone who is more in shape.


Dosage forms of Sildenafil

The dose of Sildenafil is typically taken at least 4 hours before sexual activity to allow the medication to be effective. This reduces the risk of sudden side effects. The medication is available in tablet form, and some men prefer to swallow the tablets while others prefer to take the medication as a gel inserted into the urethra. Sildenafil is also available in suppository form.

Side effects of Sildenafil

Sildenafil is generally considered to be safe. However, like all medications, there are side effects. Most of the side effects of sildenafil are mild and go away when the medication is stopped. Some people, however, may experience less common side effects, including headaches, flushing, diarrhea, and nasal congestion.


Conclusion: Sum up the article

Tadalafil and sildenafil are two of the most popular ED pills on the market, but there are differences between them that patients should be aware of. Tadalafil is more difficult to metabolize, meaning it stays in your system longer. Sildenafil is absorbed more quickly, which may work better for those who have more difficulty achieving an erection or maintaining one.

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